Deepak Kumar , Ph.D.

Scientist E and Head, Pharmacology & Drug Discovery Division
Pharmacology & Drug Discovery Division
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Research Interest

  • Phytopharmaceutical drug discovery and development
  • Bio-assay guided isolation and characterization of secondary metabolites
  • Process development and scale up
  • Analytical method development and standardization
  • NDDS based herbal formulations
  • Clean & natural ingredients

 

Credentials

  • M.S. (Pharm) Natural Products: National Institute of Pharmaceutical Education and Research, Kolkata (NIPER-Kolkata)
  • Ph.D. : Jadavpur University, Kolkata
  • Scientist: CSIR-North East Institute of Science and Technology (NEIST), Jorhat
  • Scientist C, D and E: CSIR-Indian Institute of Chemical Biology, Kolkata

Honours & Awards

  • CSIR Senior Research Fellowship, 2013.
  • DST Inspire Fellowship, 2011.
  • CSIR Senior Research Fellowship, 2010.
  • Institute medal: M.S. (Pharm.) Natural Products NIPER Kolkata.
  • Postgraduate fellowship at NIPER Kolkata.
  • GATE 2006 & 2007
  • State and national science exhibitions.

Patents & Publications

Publication from CSIR-IICB:

  1. Tripathy P, Kumar R, Darshani P, Kumar D*. Design of experiment for optimization of phenolic lipids extraction from the cashew nutshell. Ind Crops prod. 2026. 248, 123571. 
  2. Barman R, Banerjee C, Lone BA, Chakraborty C, Kumar D*. Optimizing luteolin extraction from the Pterospermum acerifolium flowers using response surface methodology and evaluation of its monoamine oxidase inhibitory potential. Results Chem. 2026. 103477. 
  3. Dahat Y, Yatham P, Kumar D*. Fabrication of Saponin-in-Surfactant nano-emulsion for improved in-vitro gastrointestinal bio-accessibility of oleanane glycosides derived from Momordica dioica fruits. J. Food Sci. Technol. 2026. 
  4. Banerjee C, Yatham P, Mukherjee S, Chakraborty J*, Kumar D*. Activity-guided isolation of sesquiterpene coumarins from Ferula assa-foetida as Monoamine oxidase inhibitors: Investigation on their therapeutic implications in a mice model of Parkinson’s disease. J. Ethnopharmacol. 2025. 120608.
  5. Dahat Y, Ganguly S, Khan A, Gajbhiye RL, Kumar D*. Optimizing ultrasonication-assisted comprehensive extraction of bioactive flavonoids from Pterocarpus santalinus leaves using response surface methodology. J. Chromatogr. A. 2024. 1738:465477. 
  6. Banerjee C, Tripathy D, Kumar D*, Chakraborty J*. Monoamine oxidase and neurodegeneration: Mechanisms, inhibitors and natural compounds for therapeutic intervention. Neurochem Int. 2024. 179:105831. 
  7. Banerjee C, Barman R, Darshani P, Pillai M, Ahuja S, Mondal R, Pragadheesh VS, Chakraborty J*, Kumar D*. α-Viniferin, a dietary phytochemical, inhibits Monoamine oxidase and alleviates Parkinson's disease associated behavioral deficits in a mice model. Neurochem Int. 2024; 174:105698. 
  8. Darshani P, Sarma SS, Tripathy P, Kumar D*. Ultrasonication-assisted optimization of pterostilbene extraction from Pterocarpus santalinus heartwood using response surface methodology. Ind Crops prod. 2024; 118409.
  9. Darshani P, Sarma SS, Gajbhiye RL, Srivastava AK, Kumar D*. Isolation, characterization, in-vitro and in-silico assessment of undescribed bioactive constituents from Pterocarpus santalinus L. heartwood. ACS Omega. 2024; 9, 50, 49013–49022.
  10. Banerjee C, Nandy S, Chakraborty J*, Kumar D*. Myricitrin - a flavonoid isolated from the Indian olive tree (Elaeocarpus floribundus) - inhibits Monoamine oxidase in the brain and elevates striatal dopamine levels: therapeutic implications against Parkinson's disease. Food Funct. 2022; 13(12):6545-6559. 
  11. Yatham P, Shukla D, Srivastava AK, Pragadheesh VS, Kumar D*. Purification and identification of anticancer organosulfides from Ferula assa-foetida gum: integrative analysis employing GC/GC-MS/RP-HPLC/NMR. Nat Prod Res. 2022; 36(11):2869-2874.
  12. Darshani P, Sen Sarma S, Srivastava AK, Baishya R, Kumar D*. Anti-viral triterpenes: a review. Phytochem Rev. 2022, 21(6):1761-1842. 
  13. Dahat Y, Saha P, Mathew JT, Chaudhary SK*, Srivastava AK*, Kumar D*. Traditional uses, phytochemistry and pharmacological attributes of Pterocarpus santalinus and future directions: A review. J Ethnopharmacol. 2021; 276:114127. 

Other Publications:

  1. Baishya, R., Nayak, D.K., Kumar, D., Sinha, S., Gupta, A., Ganguly, S., Debnath, M.C. 2016. Ursolic acid loaded PLGA nanoparticles : in vitro and in vivo evaluation to explore tumor targeting ability on B16F10 melanoma cell lines. Pharmaceutical Research, 33, 2691-2703.
  2. Saini, P., Mukherjee, N., Mukherjee, S., Roy, P., Gayen, P., Kumar, D., Pal, B.C., Babu, S.P.S. 2015. Diospyros perigrena barks extract induced apoptosis in filarial parasite Setaria cervi through generation of reactive oxygen species. Pharmaceutical Biology, 53, 813-823.
  3. Kumar, D., Tejaswi, C., Rasamalla, S., Mallick, S., Pal, .C. 2015. Bio-assay Guided Isolation of Anti-cancer Compounds from Anthocephalus cadamba Natural Product Communications, 10, 1349-1350.
  4. Saini, P., Gayen, P., Kumar, D., Nayak, A., Mukherjee, N., Mukherjee, S., Pal, B. C., Sinha Babu S. P. 2014. Antifilarial effect of ursolic acid from Nyctanthes arbortristis: molecular and biochemical evidences. Parasitology International, 63, 717-728.
  5. Mallick, S., Pal, B. C., Kumar, D., Chatterjee, N., Saha, K. D. 2013. Effect of corchorusin-D, a saikosaponin like compound, on B16F10 melanoma cells (in vitro and in vivo). Journal of Asian Natural Products Research, 15, 1197-1203.
  6. Kumar, D., Ghosh, R., Pal, B. C. 2013. α-Glucosidase inhibitory terpenoids from Potentilla fulgens and their quantitative estimation by validated HPLC method. Journal of Functional Foods, 5, 1135-1141.
  7. Kumar, D., Gupta, N., Ghosh, R., Gaonkar, R. H., Pal, B. C. 2013. α-Glucosidase and α-amylase inhibitory constituent of Carex baccans: Bio-assay guided isolation and quantification by validated RP-HPLC-DAD. Journal of Functional Foods, 5, 211-218.
  8. Kumar, D., Datta, S., Gaonkar, R. H., Roy, S. S., Vedasiromoni, J. R., Ghosh, R., Pal, B. C. 2013. Bioactivity-guided isolation and quantification of anti-diabetic principle in Holarrhena antidysenterica (Wall), in-vitro. Journal of Herbs, Spices & Medicinal Plants, 19, 54-63.
  9. Kumar, D., Shah, V., Ghosh, R., Pal, B. C. 2013. A new triterpenoid saponin from Glinus oppositifolius with α-glucosidase inhibitory activity. Natural Product Research, 27, 624-630.
  10. Kumar, D., Kumar, H., Vedasiromoni, J. R., Pal, B. C. 2012. Bio-assay guided isolation of α-glucosidase inhibitory constituents from Hibiscus mutabilis Phytochemical Analysis, 23, 421-425.
  11. Kumar, D., Gaonkar, R. H., Ghosh, R., Pal, B. C. 2012. Bio-assay guided isolation of α-glucosidase inhibitory constituents from Eclipta alba. Natural Product Communications, 7, 989-990.
  12. Saini, P., Gayen, P., Nayak, A., Kumar, D., Mukherjee, N., Pal, B. C., Sinha Babu S. P. 2012. Effect of ferulic acid from Hibiscus mutabilis on filarial parasite Setaria cervi: Molecular and biochemical approaches. Parasitology International, 61, 520-531.
  13. Mallick, S., Pal, B. C., Vedasiromoni, J. R., Kumar, D., Saha, K. D. 2012. Corchorusin-D directed apoptosis of K562 cells occurs through activation of mitochondrial and death receptor pathways and suppression of AKT/PKB pathway. Cellular Physiology and Biochemistry, 30, 915-926.
  14. Kumar, D., Mallick, S., Vedasiromoni, J. R., Pal, B. C. 2010. Anti-leukemic activity of Dillenia indica L. fruit extract and quantification of betulinic acid by HPLC. Phytomedicine, 17, 431-435.

Patents from CSIR-IICB:

  1. Kumar D, Srivastava AK, Roy SS, Sarma SS, Bose S. 2024. Composition for treating ovarian cancer and a preparation method thereof. Application number IN202411045945.
  2. Kumar D, Chakraborty J, Yatham P, Banerjee C, Sarma SS. 2023. A composition for treating Parkinson's disease. Application number IN202311006898; PCT/IN2024/050529.
  3. Das SK, Kumar D, Swarnakar S, Bose S, Dahat Y. 2021. Antimicrobial cationic metal nanoparticles conjugated nanoemulsions and process for the preparation thereof. Application number IN20211104522
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