Credentials

• M.S. (Pharm) Natural Products: National Institute of Pharmaceutical Education and Research, Kolkata (NIPER-Kolkata)
• Ph.D. : Jadavpur University, Kolkata
• Assistant Manager: Natural Product Research Lab, Venus Remedies Ltd, Panchkula
• Scientist: Research & Development, Sami Labs Ltd, Bangalore
• Sr Executive: Advanced Research Division, L’Oreal India Pvt Ltd, Bangalore
• Scientist: CSIR-North East Institute of Science and Technology (NEIST), Jorhat

Honours & Awards

• CSIR Senior Research Fellowship, 2013.
• DST Inspire Fellowship, 2011.
• CSIR Senior Research Fellowship, 2010.
• Institute medal: M.S. (Pharm.) Natural Products NIPER Kolkata.
• Postgraduate fellowship at NIPER Kolkata.
• GATE 2006 & 2007
• State and national science exhibitions.

Patents & Publications

Publication from CSIR-IICB:

1. Darshani P, Sarma SS, Tripathy P, Kumar D*. Ultrasonication-assisted optimization of pterostilbene extraction from Pterocarpus santalinus heartwood using response surface methodology. Ind Crops Prod. 2024; 118409. https://doi.org/10.1016/j.indcrop.2024.118409. (IF 5.9)
2. Darshani P, Sarma SS, Gajbhiye RL, Srivastava AK, Kumar D*. Isolation, characterization, in-vitro and in-silico assessment of undescribed bioactive constituents from Pterocarpus santalinus L. heartwood. ACS Omega. 2024; https://doi.org/10.1021/acsomega.3c10180. (IF 4.1)
3. Banerjee C, Barman R, Darshani P, Pillai M, Ahuja S, Mondal R, Pragadheesh VS, Chakraborty J*, Kumar D*. α-Viniferin, a dietary phytochemical, inhibits Monoamine oxidase and alleviates Parkinson's disease associated behavioral deficits in a mice model. Neurochem Int. 2024; 174:105698. https://doi.org/10.1016/j.neuint.2024.105698. (IF 4.2)
4. Mandal T, Shukla D, Pattanayak S, Barman R, Ashraf R, Kumar S, Kumar D, Srivastava AK*. Ellagic acid Induces DNA damage and apoptosis in cancer stem like cells via mitochondrial dysfunction mediated ROS-generation and overcomes cisplatin induced stemness. ACS Omega. 2024. Accepted Manuscript. (IF 4.1)
5. Bose S, Dahat Y, Kumar D, Haldar S, Das SK*. A membrane targeted multifunctional cationic nanoparticle conjugated fusogenic nanoemulsion (CFusoN): induced membrane depolarization and lipid solubilization to accelerate the killing of Staphylococcus aureus.  Mater Horiz. 2024, 11, 661-379. doi: 10.1039/d3mh01102j. (IF 13.3)
6. Singh CP, Sharma A, Sharma K, Darshani P, Katare A, Kumar D, Bharitkar YP*. Two new cycloartane type triterpenes from Dysoxyllum binectariferum. Nat Prod Res. 2023; 29:1-8. doi: 10.1080/14786419.2023.2172008. (IF 2.4)
7. Karmakar E, Das P, Yatham P, Kumar D*, Mukhopadhyay S, Roy SS*. Seedpod extracts of Wrightia tinctoria shows significant anti-inflammatory effects in HepG2 and RAW-264.7 cell lines. Nat Prod Res. 2022; 17:1-5. doi: 10.1080/14786419.2022.2146688. (IF 2.4)
8. Banerjee C, Nandy S, Chakraborty J*, Kumar D*. Myricitrin - a flavonoid isolated from the Indian olive tree (Elaeocarpus floribundus) - inhibits Monoamine oxidase in the brain and elevates striatal dopamine levels: therapeutic implications against Parkinson's disease. Food Funct. 2022; 13(12):6545-6559. doi: 10.1039/d2fo00734g. (IF 6.3)
9. Yatham P, Shukla D, Srivastava AK, Pragadheesh VS, Kumar D*. Purification and identification of anticancer organosulfides from Ferula assa-foetida gum: integrative analysis employing GC/GC-MS/RP-HPLC/NMR. Nat Prod Res. 2022; 36(11):2869-2874. doi: 10.1080/14786419.2021.1922903. (IF 2.4)
10. Darshani P, Sen Sarma S, Srivastava AK, Baishya R, Kumar D*. Anti-viral triterpenes: a review. Phytochem Rev. 2022, 21(6):1761-1842. doi: 10.1007/s11101-022-09808-1. (IF 7.7)
11. Dahat Y, Saha P, Mathew JT, Chaudhary SK*, Srivastava AK*, Kumar D*. Traditional uses, phytochemistry and pharmacological attributes of Pterocarpus santalinus and future directions: A review. J Ethnopharmacol. 2021; 276:114127. doi: 10.1016/j.jep.2021.114127. (IF 5.1)

Other Publications:

1. Baishya, R., Nayak, D.K., Kumar, D., Sinha, S., Gupta, A., Ganguly, S., Debnath, M.C. 2016. Ursolic acid loaded PLGA nanoparticles : in vitro and in vivo evaluation to explore tumor targeting ability on B16F10 melanoma cell lines. Pharmaceutical Research, 33, 2691-2703.
2. Saini, P., Mukherjee, N., Mukherjee, S., Roy, P., Gayen, P., Kumar, D., Pal, B.C., Babu, S.P.S. 2015. Diospyros perigrena barks extract induced apoptosis in filarial parasite Setaria cervi through generation of reactive oxygen species. Pharmaceutical Biology, 53, 813-823.
3. Kumar, D., Tejaswi, C., Rasamalla, S., Mallick, S., Pal, .C. 2015. Bio-assay Guided Isolation of Anti-cancer Compounds from Anthocephalus cadamba Natural Product Communications, 10, 1349-1350.
4. Saini, P., Gayen, P., Kumar, D., Nayak, A., Mukherjee, N., Mukherjee, S., Pal, B. C., Sinha Babu S. P. 2014. Antifilarial effect of ursolic acid from Nyctanthes arbortristis: molecular and biochemical evidences. Parasitology International, 63, 717-728.
5. Mallick, S., Pal, B. C., Kumar, D., Chatterjee, N., Saha, K. D. 2013. Effect of corchorusin-D, a saikosaponin like compound, on B16F10 melanoma cells (in vitro and in vivo). Journal of Asian Natural Products Research, 15, 1197-1203.
6. Kumar, D., Ghosh, R., Pal, B. C. 2013. α-Glucosidase inhibitory terpenoids from Potentilla fulgens and their quantitative estimation by validated HPLC method. Journal of Functional Foods, 5, 1135-1141.
7. Kumar, D., Gupta, N., Ghosh, R., Gaonkar, R. H., Pal, B. C. 2013. α-Glucosidase and α-amylase inhibitory constituent of Carex baccans: Bio-assay guided isolation and quantification by validated RP-HPLC-DAD. Journal of Functional Foods, 5, 211-218.
8. Kumar, D., Datta, S., Gaonkar, R. H., Roy, S. S., Vedasiromoni, J. R., Ghosh, R., Pal, B. C. 2013. Bioactivity-guided isolation and quantification of anti-diabetic principle in Holarrhena antidysenterica (Wall), in-vitro. Journal of Herbs, Spices & Medicinal Plants, 19, 54-63.
9. Kumar, D., Shah, V., Ghosh, R., Pal, B. C. 2013. A new triterpenoid saponin from Glinus oppositifolius with α-glucosidase inhibitory activity. Natural Product Research, 27, 624-630.
10. Kumar, D., Kumar, H., Vedasiromoni, J. R., Pal, B. C. 2012. Bio-assay guided isolation of α-glucosidase inhibitory constituents from Hibiscus mutabilis Phytochemical Analysis, 23, 421-425.
11. Kumar, D., Gaonkar, R. H., Ghosh, R., Pal, B. C. 2012. Bio-assay guided isolation of α-glucosidase inhibitory constituents from Eclipta alba. Natural Product Communications, 7, 989-990.
12. Saini, P., Gayen, P., Nayak, A., Kumar, D., Mukherjee, N., Pal, B. C., Sinha Babu S. P. 2012. Effect of ferulic acid from Hibiscus mutabilis on filarial parasite Setaria cervi: Molecular and biochemical approaches. Parasitology International, 61, 520-531.
13. Mallick, S., Pal, B. C., Vedasiromoni, J. R., Kumar, D., Saha, K. D. 2012. Corchorusin-D directed apoptosis of K562 cells occurs through activation of mitochondrial and death receptor pathways and suppression of AKT/PKB pathway. Cellular Physiology and Biochemistry, 30, 915-926.
14. Kumar, D., Mallick, S., Vedasiromoni, J. R., Pal, B. C. 2010. Anti-leukemic activity of Dillenia indica L. fruit extract and quantification of betulinic acid by HPLC. Phytomedicine, 17, 431-435.

Patents from CSIR-IICB:

1. Das SK, Kumar D, Swarnakar S, Bose S, Dahat Y. 2021. Antimicrobial cationic metal nanoparticles conjugated nanoemulsions and process for the preparation thereof. Application number 202111045225.
2. Kumar D, Chakraborty J, Yatham P, Banerjee C, Sarma SS. 2023. A composition for treating Parkinson's disease. Application number 202311006898.
3. Kumar D, Srivastava AK, Roy SS, Sarma SS, Bose S. 2024. Composition for treating ovarian cancer and a preparation method thereof. Application number 202411045945.
4. Kumar D, Chakraborty J, Yatham P, Banerjee C, Sarma SS. 2024. A composition for treating Parkinson's disease. Application number PCT/IN2024/050529.