Structural Biology & Bio-Informatics Division

Vision

Structure-function analysis of various biological macromolecules using multi-pronged approaches from different angles involving modern biological, chemical and physical technologies.

Objectives

  • Characterisation of potentially prospective biological macromolecules and other small molecules of therapeutic interest against various diseases, e.g. leishmania, cholera, cancer, diabetes and for other anti-inflamatory, anticonvulsant and immunomodulatory activities.
  • Studies on protein-protein and protein-nucleic acid interactions applying modern sophisticated technologies like nuclear magnetic resonance (NMR), mass-spectrometry.
  • Quantitative structure activity relationship (QSAR) and 3D-QSAR.
  • Development of software for prediction, modification and analysis of macromolecular structures and for elucidating their interactions with bio-active molecules.

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