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Structural Biology & Bio-Informatics Division

Dr. Debasish Bhattacharyya

Chief Scientist
Ph. D. Calcutta University, 1986
Contact - debasish@iicb.res.in

Tel: 033-4933-5764 (direct)

Current Research Interest

  • Enzyme kinetics and stability of proteins.
  • Toxicological studies of venom proteins and
  • Chemical analysis of drugs and their mechanism of action.

10 years (1999 - 2009) of Industrial Partnership with M/S Albert Devid Ltd., Calcutta.

Names of the group members including regular staff with designation and research fellows:
Fellow/RA Staff
  1. Ms Debashree De (SRF/CSIR)
  2. Ms Nupur Sengupta (SRF/UGC-NET)
  3. Ms Debratna Saha (SRF/DST)
  4. Mr Jyotirmoy Mitra (JRF/CSIR)
  5. Ms Anwesha Majumdar (SRF/Drug House Project)
  6. Ms Payel Bhattacharjee (JRF/UGC-NET)
  7. Ms. Kanika Sharma, (JRF/UGC)
Mr Samir K Roy, Technical Officer (associated also with Dr Syamal Roy)

List of important Publications:

  1. Brahma, A. and Bhattacharyya, D. (2004) UDP-galactose 4-epimerase from Kluveromyces fragilis: Evidence for independent mutarotase site. Eur. J. Biochem. 271, 58-68.
  2. Nayar, S., Brahma, A., Barat, B. and Bhattacharyya, D. (2004) UDP-galactose 4-epimerase from Kluveromyces fragilis: Analysis of its hysteretic behavior in catalysis. Biochemistry 43, 10212-10223.
  3. Brahma, A. and Bhattacharyya, D. (2004) UDP-galactose 4-epimerase from Kluveromyces fragilis: Existence of subunit independent functional site. FEBS Lett. 577, 27-34.
  4. Datta, P. and Bhattacharyya, D. (2004) Spectroscopic and chromatographic evidences of NADPH in human placental extract used as wound healer. J. Pharma. Biomed. Anal. 34, 1091-1098.
  5. Datta, P. and Bhattacharyya, D. (2004) Analysis of excitation-emission fluorescence matrix for multi component drugs: A case study with human placental extract used as wound healer. J. Pharma. Biomed. Anal. 36, 211-218.
  6. Datta - Chakrabarty, P. and Bhattacharyya, D. (2005) Purification of fibronectin type III in human placental extract used as wound healer. J. Chromatogr. B.  818, 67-73.
  7. Brahma, A., Mandal, C. and Bhattacharyya, D. (2005) Characterization of a dimeric unfolded state of Bovine Serum Albumin under mildly acidic conditions. Biochim. Biophys. Acta 1751, 159-169.
  8. Mandal, S. and Bhattacharyya, D. (2007) Ability of a small basic protein from Russell’s viper venom to induce renal tubular necrosis in mice. Toxicon 50, 236-250.
  9. Mandal, S. and Bhattacharyya, D. (2008) Two L-amino acid oxidase isoenzymes from Russell’s viper (Daboia russelli russelli) venom with different mechanisms of inhibition by substrate analogs FEBS J. 275, 1078-1095.
  10. Bhattacharya, R. and Bhattacharyya, D. (2009) Stability of Bromelain from pineapple (Ananus cosmos). J. Food Biochem.33, 1-19.
  11. Bhattacharya, R. and Bhattacharyya, D. (2009) Resistance of Bromelain to SDS binding. Biochem. Biophys. Acta 1794, 698-708.
  12. De, D., Datta-Chakrabarty, P and Bhattacharyya, D (2009) Analysis of free and bound NADPH in aqueous extract of human placenta used as wound healer. J. Chromat. B. 877, 2435-2442.
  13. Brahma, A., Banerjee, N. and Bhattacharyya, D. (2009) UDP-galactose 4-epimerase from Kluyveromyces fragilis: Catalytic sites of the homodimeric enzyme are functional and regulated. FEBS J. 276, 6725-6740
  14. Chakraborty, P.D., De, D., Bandyopadhyay, S. and Bhattacharyya, D. (2009) Human aqueous placental extract as a wound healer. J. Wound Care 18, 462-467.

Detail list of Publications upto December'2010 ==>> Click here

 

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Updated on 12.11.2009
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