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Structural Biology & Bio-Informatics Division

Dr. Chitra Dutta ( Head )

Dr. Chitra Dutta ( Head )

Sr. Principal Scientist
PhD, Calcutta University,1984

Contact - cdutta@iicb.res.in

Current Research Interest

  • Computational analysis of microbial genome sequences with a view to study.
    • Trends and anomalies in nucleotide/amino acid usage patterns in eubacteria, archaea and viruses.
    • Codon adaptation in extremophiles.
    • Evolution of bacterial pathogenesis through gene loss/acquisition.
  • In silico characterization of the selection forces governing protein composition in human.
  • Clustering of protein families & taxonomic distribution of domains.
  • Development of novel software tools or algorithms for genome / proteome analysis.
 
Names of the group members including regular staff with designation and research fellows:
Fellow/RA Staff Others
  1. Ms. Ipsita Chanda, SRF, CSIR
  2. Mr. Anirban Dutta, JRF, CSIR-GATE
  3. Ms. Munmun Sarkar, JRF, CSIR-GATE
  1. Ms. Subhagata Ghosh, Technical Officer
  1. Mr. Sanjib Chatterjee
  2. Mr. Sandip Paul
  3. Mr. Sumit Das

List of important Publications:

  • Das S, Paul S, Bag S. K., Dutta C.
    Analysis of Nanoarchaeum equitans genome and proteome composition: Indications for hyperthermophilic and parasitic adaptation. BMC Genomics. 2006; 7:186
  • Das S, Paul S, Dutta C.
    Evolutionary constraints on codon and amino acid usage in two strains of human pathogenic Actinobacteria Tropheryma whipplei. J Mol Evol. 2006; 62(5):645-58
  • Das S, Paul S, Dutta C.
    Synonymous codon usage in Adenoviruses: Influence of mutation, selection and protein hydropathy. Virus Res. 2005;117(2):227-36.
  • Das S, Paul S, Chatterjee S, Dutta C.
    Codon and amino Acid usage in two major human pathogens of genus Bartonella - Optimization between replicational-transcriptional selection, translational control and cost minimization. DNA Res. 2005; 12(2):91-102.
  • Chanda I, Pan A, Dutta C.
    Proteome composition in Plasmodium falciparum: Higher usage of GC-rich nonsynonymous codons in highly expressed genes. J Mol Evol. 2005; 61(4):513-23.
  • Das S, Ghosh S, Pan A, Dutta C.
    Compositional variation in bacterial genes and proteins with potential expression level. FEBS Lett. 2005;579(23):5205-10.
  • Das S, Pan A, Paul S, Dutta C.
    Comparative analyses of codon and amino acid usage in symbiotic island and core genome in nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum. J Biomol Struct Dyn. 2005;23(2):221-32.
  • Pan A, Dutta C, Das J.
    Codon usage in highly expressed genes of Haemophillus influenzae and Mycobacterium tuberculosis: translational selection versus mutational bias.
  • Basu S, Pan A, Dutta C, Das J.
    Chaos game representation of proteins.
    J Mol Graph Model. 1997;15(5):279-89
  • Dutta C, Das J.
    Mathematical characterization of Chaos Game Representation. New algorithms for nucleotide sequence analysis. J Mol Biol. 1992 ; 228(3):715-9.

Detail list of Publications upto December'2010 ==>> Click here

 
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Updated on 16th March'2011
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