Structural Biology & Bio-Informatics Division

Dr. Chitra Dutta

PhD, Calcutta University,1984

Contact: cdutta@iicb.res.in

Chief Scientist & Head

Current Research Interest

  • Computational analysis of microbial genome sequences with a view to study.
    • Trends and anomalies in nucleotide/amino acid usage patterns in eubacteria, archaea and viruses.
    • Codon adaptation in extremophiles.
    • Evolution of bacterial pathogenesis through gene loss/acquisition.
  • In silico characterization of the selection forces governing protein composition in human.
  • Clustering of protein families & taxonomic distribution of domains.
  • Development of novel software tools or algorithms for genome / proteome analysis.

Names of the group members including regular staff with designation and research fellows

Staff

  1. Ms. Subhagata Ghosh, Technical Officer
  2. Dr.(Mrs.) Aparna Laskar , Technical Officer

 

Fellows / RA

  1. Ms. Ipsita Chanda, SRF, CSIR
  2. Mr. Anirban Dutta, JRF, CSIR-GATE
  3. Ms. Munmun Sarkar, JRF, CSIR-GATE

Others

  1. Mr. Sanjib Chatterjee
  2. Mr. Sandip Paul
  3. Mr. Sumit Das

List of important Publications

  1. Das S, Paul S, Bag S. K., Dutta C.
    Analysis of Nanoarchaeum equitans genome and proteome composition: Indications for hyperthermophilic and parasitic adaptation. BMC Genomics. 2006; 7:186
  2. Das S, Paul S, Dutta C.
    Evolutionary constraints on codon and amino acid usage in two strains of human pathogenic Actinobacteria Tropheryma whipplei. J Mol Evol. 2006; 62(5):645-58
  3. Das S, Paul S, Dutta C.
    Synonymous codon usage in Adenoviruses: Influence of mutation, selection and protein hydropathy. Virus Res. 2005;117(2):227-36.
  4. Das S, Paul S, Chatterjee S, Dutta C.
    Codon and amino Acid usage in two major human pathogens of genus Bartonella - Optimization between replicational-transcriptional selection, translational control and cost minimization. DNA Res. 2005; 12(2):91-102.
  5. Chanda I, Pan A, Dutta C.
    Proteome composition in Plasmodium falciparum: Higher usage of GC-rich nonsynonymous codons in highly expressed genes. J Mol Evol. 2005; 61(4):513-23.
  6. Das S, Ghosh S, Pan A, Dutta C.
    Compositional variation in bacterial genes and proteins with potential expression level. FEBS Lett. 2005;579(23):5205-10.
  7. Das S, Pan A, Paul S, Dutta C.
    Comparative analyses of codon and amino acid usage in symbiotic island and core genome in nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum. J Biomol Struct Dyn. 2005;23(2):221-32.
  8. Pan A, Dutta C, Das J.
    Codon usage in highly expressed genes of Haemophillus influenzae and Mycobacterium tuberculosis: translational selection versus mutational bias.
  9. Basu S, Pan A, Dutta C, Das J.
    Chaos game representation of proteins.
    J Mol Graph Model. 1997;15(5):279-89
  10. Dutta C, Das J.
    Mathematical characterization of Chaos Game Representation. New algorithms for nucleotide sequence analysis. J Mol Biol. 1992 ; 228(3):715-9.
 
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Updated on 16th March'2011


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