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Molecular & Human Genetics Division

Dr. Suvendra Nath Bhattacharyya

Senior Scientist
PhD, Jadavpur University,Kolkata,West Bengal,India,2003

International Senior Research Fellow, The Wellcome trust London & Career Development Awardee of the International Human Frontier Science Program Organization

2004-2008:   HFSPO Post-Doctoral Research Fellow at Friedrich Miescher Institute, Basel, Switzerland
         2004:   AAAS/Science-GE healthcare Young Scientist Award, USA
                     and  INSA Young Scientist award, INDIA
1998-2003: Research Fellow, Indian Institute of Chemical Biology, Calcutta, India

Contact - suvendra@iicb.res.in / suvendrab@yahoo.com

Current Research Interest

  1. Effect of cellular microenvironment on miRNA-mediated gene regulation in mammalian cells.
  2. Role of host cell miRNAs and other post-transcriptional factors in regulation of parasitic infection of mammalian cells
  3. Mechanism of mRNA compartmentalization to translationally active polyribosomes and translationally inactive RNP-granules/P-bodies in mammalian cells.
Names of the group members including regular staff with designation and research fellows:
Laboratory Members: (Post-Doctoral Fellow) Fellow/RA/PA
  1. Dr. Sudarshana Basu (RA, DBT)
  2. Dr. Hrishikesh Sil (RA, DBT)
  1. Mr. Anup Mazumder (SRF, CSIR)
  2. Mr. Souvik Ghosh (SRF, CSIR)
  3. Mrs. Kamalika Mukherjee (SRF)
  4. Ms. Bahnnisikha Barman (JRF, CSIR)
  5. Ms. Somi Patranabis (JRF, CSIR)
  6. Mr. Yogaditya Chakraborty (JRF, CSIR)
  7. Mr. Mainak Bose (SPM Fellow, CSIR)
  8. Bartika Ghoshal (JRF, CSIR)

List of important Publications:

  1. Mazumder, A., Bose, M., Chakraborti, A., Chakrabarti, S. and Bhattacharyya, S.N., (2013). A transient reversal of miRNA-mediated repression controls macrophage activation. EMBO Rep. (in press).
  2. Ghosh, J., Bose, M., Roy, S., Bhattacharyya, S.N., (2013). Leishmania donovani Targets Dicer1to Downregulate miR-122, Lower Serum Cholesterol, and Facilitate Murine Liver Infection. Cell Host Microbe, 13, 277-288.
  3. Kundu, P., Fabian, M.R., Sonenberg, N., Bhattacharyya, S.N.*, Filipowicz, W*., (2012). HuR protein attenuates miRNA-mediated repression by promoting miRISC dissociation from the target RNA. Nucleic Acids Res., 40, 5088-6000.
  4. Cougot, N*., Bhattacharyya, S.N*., Tapia-Arancibia, L., Bordonné R., Filipowicz, W., Bertrand E., and Rage, F., (2008). Dendrites of mammalian neurons contain specialized P-body-like structures that respond to neuronal activation. J. Neuroscience, 28, 13793-13804.
  5. Filipowicz, W., Bhattacharyya, S.N., Sonenberg, N., (2008). Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet., 9, 102-114.
  6. Bhattacharyya, S.N., & Filipowicz W., (2007). Argonautes and company: sailing against the wind. Cell, 128, 1027-1028.
  7. Pillai, R.S., Bhattacharyya, S.N., & Filipowicz W., (2007). Repression of protein synthesis by miRNAs: How many mechanisms? Trends in Cell Biology, 17, 118-126.
  8. Bhattacharyya, S.N., Habermacher, R., Martine, U., Closs, E.I., & Filipowicz, W., (2006). Relief of microRNA-mediated translational repression in human cells subjected to stress. Cell, 125, 1111-1124.
  9. Kotaja, N*., Bhattacharyya, S.N*., Jaskiewicz, L, Kimmins, S, Parvinen, M, Filipowicz, W., & Sassone-Corsi, P., (2006). The chromatoid body of male germ cells: Similarity with processing bodies and presence of Dicer and microRNA pathway components. Proc. Natl. Acad. Sci. U S A., 103, 2647-2652.
  10. Pillai, R.S., Bhattacharyya, S.N., Artus, C.G., Zoller, T., Cougot, N., Basyuk, E., Bertrand, E. & Filipowicz W., (2005). Inhibition of translational initiation by let-7 microRNA in human cells. Science, 309, 573-1576.

Detail list of Publications upto August 2013 ==>> Click here



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Updated on 13th September 2013
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