Molecular & Human Genetics Division

Dr. Keya Chaudhuri

PhD, Jadavpur University,1983

Contact: kchaudhuri@iicb.res.in


Chief Scientist & Head

KC Group Lab Website

Current Research Interest

  • Interaction of Vibrio cholerae and its outer membrane vesicles with host cells
  • Identification of risk genotypes and biomarkers associated with precancerous oral submucous fibrosis
  • Development of bioinformatics tools and their application to identification of new virulence factors in pathogenic organisms
  • Remediation of chronic arsenic toxicity by herbal compounds

Names of the group members including regular staff with designation and research fellows

 

Fellows / RA

  1. Avirup Dutta, SRF
  2. Sanjit Mukherjee, SRF
  3. Debashree Chatterjee, SRF
  4. Pallashri Saha, SRF
  5. Samir Mandal, SRF
  6. Bornita Das, SRF
  7. Mr Atul Kishorrao Katarkar, SRF(ICMR)

Others

Dr. Tapasi Das, Principal Investigator (DST)(WOS-A)

 

List of important Publications

  1. Saha P, Das B and Chaudhuri K*. (2013). Role of 6-Gingerol in the reduction of cholera toxin activity in vitro and in vivo. Antimicrobial Agents Chemotherapy Jul 1. [Epub ahead of print]
  2. Chatterjee D, Chaudhuri K*. (2013). Vibrio cholerae O395 outer membrane vesicles modulate intestinal epithelial cells in a NOD1 dependent manner and induces dendritic cell-mediated Th2/Th17 responses. Journal of Biological Chemistry 288(6):4299-309
  3. Dutta A, Katarkar A, Chaudhuri K*. (2013). In-Silico structural and functional characterization of a V. cholerae O395 Hypothetical Protein Containing a PDZ1 and an Uncommon Protease Domain. PLoS ONE 8(2): e56725.
  4. Mandal S, Hossain M, Devi P. Sujatha, Kumar GS, Chaudhuri K*. (2013).Interaction of carbon nanoparticles to serum albumin: elucidation of the extent of perturbation of serum albumin conformations and thermodynamical parameters. Journal of Hazardous Materials 248– 249: 238– 245
  5. Sarkar M, Bhowmick S, Casola A, Chaudhuri K*. (2012). Interleukin-8 gene regulation in epithelial cells by Vibrio cholerae: Role of multiple promoter elements, adherence and motility of bacteria and host MAPKs. FEBS Journal Apr;279(8):1464-1473
  6. Bhowmick S, Chatterjee D and Chaudhuri K*.(2012).  Human epithelial cells stimulated with Vibrio cholerae produce thymic stromal lymphopoetin and promote dendritic cell-mediated inflammatory Th2 response. International Journal of Biochemistry & Cell Biology  44: 1779-1790
  7. Mukherjee S, Bhowmik AD, Roychoudhury P, Mukhopadhyay K, Ray JG, Chaudhuri K*. (2012). Association of XRCC1, XRCC3, and NAT2 polymorphisms with the risk of oral submucous fibrosis among eastern Indian population. J Oral Pathol Med. 2012 Apr;41(4):292-302
  8. Chatterjee D and Chaudhuri K*. (2011). Association of cholera toxin with Vibrio cholerae outer membrane vesicles which are internalized by human intestinal epithelial cells. FEBS Letters 585:1357-1362
  9. On detection and assessment of statistical significance of Genomic Islands. (2008) Chatterjee R, Chaudhuri K and Chaudhuri P. BMC Genomics 9:150
  10. In vitro and in vivo reduction of sodium arsenite induced toxicity by aqueous garlic extract. (2008). Rajdeep Chowdhury, Abhishek Dutta, Susri Ray Chaudhuri, Nilendu Sharma, Ashok K. Giri and Keya Chaudhuri. Food Chem Technol. 46(2):740-751
 
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Updated on 12th July' 2013


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