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Infectious
Diseases & Immunology Division
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Dr. Uday Bandyopadhyay
Senior Scientist
- Ph.D Jadavpur University, Calcutta, (1994)
- Post-doctoral Fellow (1995-1996) INSERM-U99, Paris, France
- Post-doctoral Fellow (1996-1997), Humboldt Fellowship (Alexander Von Humboldt Foundation,), University of Hamburg,Germany
- Fellow of The National Academy of Sciences, India (FNASc)
Contact- ubandyo_1964@yahoo.com; udayb@iicb.res.in |
Current
Research Interest:
Malaria
- The exploration of Plasmodium falciparum proteome to identify new drug target
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Biochemistry and Molecular Biology of malaria parasite
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Host- Parasite interaction and the assessment of organ dysfunction and apoptosis during malarial infection
Gastric ulcer
- Identification of the signaling pathways for gastric mucosal apoptosis in H. pylori-mediated and non-mediated gastric ulcer.
- Identification of novel antioxidant-antiapoptotic molecule from natural sources to treat gastric ulcer
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Names
of the group members including regular staff
with designation and research fellows:
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| JRF/SRF/RA |
Staff |
- Athar Alam (SRF)
- Manish Goyal (SRF)
- Sumanta Dey (SRF)
- Chinmay Pal (SRF)
- Md. Shameel Iqbal (SRF)
- Samik Bindu (SRF)
- Souvik Sarkar (JRF)
- Rahul Kumar (JRF)
- Somnath Mazumder (JRF)(CSIR)
- Asim Azhar Siddiqui (JRF)(CSIR)
- Chinmoy Banerjee (JRF)(UGC)
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Tapan Chakraborty T.O. |
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List
of important Publications :
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Tryptamine-gallic acid hybrid prevents non-steroidal anti-inflammatory drug-induced gastropathy: Correction of mitochondrial dysfunction and inhibition of apoptosis in gastric mucosal cells. Pal C, Bindu S, Dey S, Alam A, Goyal M, Iqbal MS, Sarkar S, Kumar R, Halder KK, Debnath MC, Adhikari S, Bandyopadhyay U. J Biol Chem. 2011, Dec 7, [PMID: 22157011 ]
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Translocation of heme oxygenase-1 to mitochondria is a novel cytoprotective mechanism against non-steroidal anti-inflammatory drug-induced mitochondrial oxidative stress, apoptosis and gastric mucosal injury. Bindu S, Pal C, Dey S, Goyal M, Alam A, Iqbal MS, Dutta S, Sarkar S, Kumar R, Maity P, Bandyopadhyay U. J Biol Chem. 286, 39387-39402, 2011.
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Cysteine-3 and cysteine-4 are essential for the thioredoxin-like oxidoreductase and antioxidant activities of Plasmodium falciparum macrophage migration inhibitory factor. Alam A, Goyal M, Iqbal MS, Bindu S, Dey S, Pal C, Maity P, Mascarenhas NM, Ghoshal N, Bandyopadhyay U. Free. Radic. Biol. Med , 50 (2011) 1659–1668
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Gallic acid prevents non-steroidal anti-inflammatory drug-induced gastropathy in rat by blocking oxidative stress and apoptosis. Chinmay Pal, Samik Bindu, Sumanta Dey, Athar Alam, Manish Goyal, Mohd.Shameel Iqbal, Pallab Maity, Susanta S. Adhikari, Uday Bandyopadhyay. Free. Radic. Biol. Med. 49, (2010) 258-267
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Indomethacin, a non-steroidal anti-inflammatory drug, develops gastropathy by inducing reactive oxygen species-mediated mitochondrial pathology and associated apoptosis in gastric mucosa: A novel role of mitochondrial aconitase oxidation. Maity P, Bindu S, Dey S, Goyal M, Alam A, Pal C, Mitra K, Bandyopadhyay U. J. Biol. Chem. 284: (2009),3058-3068.
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Lansoprazole protects and heals gastric mucosa from non-steroidal anti-inflammatory drug (NSAID)-induced gastropathy by inhibiting mitochondrial as well as Fas-mediated death pathway with concurrent induction of mucosal cell renewal. P Maity, S. Bindu,V Choubey, A. Alam, K. Mitra, M. Goyal, S. Dey, M Guha, C. Pal and U Bandyopadhyay. J. Biol. Chem , 283 : (2008), 14391-14401.
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Apoptosis in liver during malaria: Role of oxidative stress and implication of mitochondrial pathway. Mithu Guha, Sanjay Kumar, Vinay Choubey, Pallab Maity and Uday Bandyopadhyay (2006). FASEB. J, 20, 1224-1226.
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Clotrimazole Inhibits Hemo- peroxidase of P. falciparum and Induces Oxidative Stress: PROPOSED ANTIMALARIAL MECHANISM OF CLOTRIMAZOLE. Vishal Trivedi ,Prem Chand, Kumkum Srivastava, Sunil K. Puri, Prakas R. Maulik, and Uday Bandyopadhyay (2005) J. Biol. Chem. 280, 41129-41136.
Detail list of Publications upto December'2010 ==>> Click here
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