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Infectious
Diseases & Immunology Division
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| Dr. Uday Bandyopadhyay |
| Scientist |
| Ph.D Jadavpur University, Calcutta, (1994) |
| Post-doctoral Fellow (1995-1996) INSERM-U99, Paris, France |
Post-doctoral Fellow (1996-1997), Humboldt Fellowship (Alexander Von Humboldt Foundation,), University of Hamburg,Germany Fellow of The National Academy of Sciences, India (FNASc)
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Contact- ubandyo_1964@yahoo.com; udayb@iicb.res.in
Current
Research Interest: Kindly visit the Lab Page
Malaria
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The exploration of Plasmodium falciparum proteome to identify new drug target
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Biochemistry and Molecular Biology of malaria parasite
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Host- Parasite interaction and the assessment of organ dysfunction and apoptosis during malarial infection
Gastric ulcer
- Identification of the signaling pathways for gastric mucosal apoptosis in H. pylori-mediated and non-mediated gastric ulcer.
- Identification of novel antioxidant-antiapoptotic molecule from natural sources to treat gastric ulcer
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Names
of the group members including regular staff
with designation and research fellows:
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| JRF/SRF/RA |
Staff |
- Athar Alam (SRF)
- Manish Goyal (SRF)
- Sumanta Dey (SRF)
- Chinmay Pal (SRF)
- Samik Bindu (JRF)
- Sourav Koley (JRF)
- Mhd Sameel Iqbal (Project Assistant)
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Tapan Chakraborty T.O. |
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List
of important Publications :
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Indomethacin, a non-steroidal anti-inflammatory drug, develops gastropathy by inducing reactive oxygen species-mediated mitochondrial pathology and associated apoptosis in gastric mucosa: A novel role of mitochondrial aconitase oxidation. Maity P, Bindu S, Dey S, Goyal M, Alam A, Pal C, Mitra K, Bandyopadhyay U. J. Biol. Chem. 284: (2009),3058-3068.
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Malarial infection develops mitochondrial pathology and mitochondrial oxidative stress to promote hepatocyte apoptosis. Sumanta Dey, Mithu Guha, Athar Alam, Manish Goyal, Samik Bindu, Chinmay Pal, Pallab Maity, Kalyan Mitra and Uday Bandyopadhyay. Free. Radic. Biol. Med. 46:(2009), 271-281
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Lansoprazole protects and heals gastric mucosa from non-steroidal anti-inflammatory drug (NSAID)-induced gastropathy by inhibiting mitochondrial as well as Fas-mediated death pathway with concurrent induction of mucosal cell renewal. P Maity, S. Bindu,V Choubey, A. Alam, K. Mitra, M. Goyal, S. Dey, M Guha, C. Pal and U Bandyopadhyay. J. Biol. Chem , 283 : (2008), 14391-14401.
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Bilirubin inhibits Plasmodium falciparum growth through the generation of reactive oxygen species. S Kumar, M Guha, V Choubey, P Maity, K Shrivastava, S K Puri and U Bandyopadhyay. Free. Radic. Biol. Med. 44: (2008), 602-613.
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Antiplasmodial activity of [(Aryl)arylsulfanylmethyl]Pyridine S Kumar, S K Das,S Dey,P Maity, M Guha, V Choubey, G Panda, and U Bandyopadhyay. Antimicrob Agents Chemother. 52: (2008), 705-715.
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Inhibition of Plasmodium falciparum choline kinase by hexadecyltrimethylammonium bromide: A possible antimalarial mechanism of hexadecyltrimethylammonium bromide. V Choubey, P Maity, M Guha, S Kumar, K Shrivastava, S K Puri and U Bandyopadhyay. Antimicrob Agents Chemother. 51: (2007), 696-706.
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Molecular characterization and localization of Plasmodium falciparum choline kinase. Choubey, V., Guha, M., Maity, M., Kumar, S., Raghunandan, R., Maulik, P. R., Mitra, K., Halder, U. C. and Uday Bandyopadhyay (2006). Biochim. Biophys. Acta. 1760, 1027-1038.
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Apoptosis in liver during malaria: Role of oxidative stress and implication of mitochondrial pathway. Mithu Guha, Sanjay Kumar, Vinay Choubey, Pallab Maity and Uday Bandyopadhyay (2006). FASEB. J, 20, 1224-1226.
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Clotrimazole Inhibits Hemo- peroxidase of P. falciparum and Induces Oxidative Stress: PROPOSED ANTIMALARIAL MECHANISM OF CLOTRIMAZOLE. Vishal Trivedi ,Prem Chand, Kumkum Srivastava, Sunil K. Puri, Prakas R. Maulik, and Uday Bandyopadhyay (2005) J. Biol. Chem. 280, 41129-41136.
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A novel antioxidant and antiapoptotic role of omeprazole to block gastric ulcer through scavenging of hydroxyl radical. K Biswas, Bandyopadhyay U, I. Chatterjee , A. Varadaraj, E. Ali and Banerjee R. K (2003). J. Biol. Chem., 278, 10990- 11001.
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