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Infectious Diseases & Immunology Division

Dr. Nahid Ali

Scientist F
PhD, Calcutta University, 1985
Contact - nali@iicb.res.in

Current Research Interest

  • Diagnostic tools for kala-azar and PKDL.
  • Mechanism of immune regulation and drug induced immunomodulation in Indian kala-azar and PKDL.
  • Evaluation of vaccination strategies and protein- and DNA-based candidate antigens.
  • Studies on immune stimulation pathways by liposomal vaccines.
  • Cationic liposome based combination therapy with existing drugs and novel compounds.

 

Names of the group members including regular staff with designation and research fellows:

 
Fellow/RA
 
  1. Ms.Smriti Mondal (Extended SRF-CSIR)
  2. Mr.Saumyabrata Mazumder (SRF-CSIR)
  3. Ms.Amrita Das (JRF-CSIR)
  4. Md. Asad (JRF-ICMR)
  5. Md. Shadab (JRF-CSIR)
  6. Mr. Sarfaraz Ahmad Ejazi (JRF-CSIR)
  7. Ms.Manjarika De (Project Assistant-DST)
  8. Ms.Roma Sinha (Project Assistant-CSIR Net work Project)
  9. Mr.Pradyot Bhattacharya (CSIR Net work Project)

List of important Publications:

  1. Sinha R, Sengupta A, Ali N and Gupta P. N. Is PGL-I really a specific antigen for leprosy? Clinical Infectious Diseases. 2010. 50:937-8.
  2. Bhowmick S, Mazumdar T, Sinha R and Ali N. Comparison of liposome based antigen delivery systems for  protection against Leishmania donovani. Journal of Controlled Release. 2010.141:199-207.
  3. Bhowmick S., and Ali N. Identification of novel Leishmania donovani antigens that help define correlates of vaccine-mediated protection in visceral leishmaniasis. PLoS ONE. 2009. 4: e5820 1-10.
  4. Veerareddy P. R., Vobalaboina V. and Ali N. Antileishmanial activity, pharmacokinetics and tissue distribution studies of mannose-grafted amphotericin B lipid nanospheres. Journal of Drug Targeting. 2009. 17: 140-7
  5. Bhowmick S., Mazumdar T., and Ali N. Vaccination route that induces transforming growth factor beta production fails to elicit protective immunity against Leishmania donovani infection. Infection and Immunity. 2009. 77:1514-23.
  6. Banerjee A., De M., and Ali, N. Complete cure of experimental visceral      leishmaniasis with amphotericin B in stearylamine-bearing cationic liposomes involves down-regulation of IL-10 and favorable T cell responses. Journal of Immunology. 2008.  181:1386-1398.
  7. Bhowmick S., and Ali, N. Recent developments in leishmaniasis vaccine delivery systems. Expert Opinion on Drug Delivery. 2008. 7:789-803.
  8. Roychoudhury J., and Ali N. Sodium Stibogluconate:Therapeutic use in the management of leishmaniasis. Indian Journal of Biochemistry and Biophysics.2008. 45: 16-22.
  9. Bhowmick S., Ravindran R., and Ali, N. Gp63 in stable cationic liposomes confers sustained vaccine immunity to susceptible BALB/c mice infected with Leishmania donovani. Infection and Immunity. 2008. 76:1003-1015. 
  10. Palit P. and Ali N. Oral therapy with sertraline, a selective serotonin reuptake  inhibitor, shows activity against Leishmania donovani. Journal of Antimicrobial Chemotherapy. 2008. 61:1120-1124.
  11. Banerjee A., Roychoudhury J., and Ali, N. Stearylamine-bearing cationic liposomes kill Leishmania parasites through surface exposed negatively charged phosphatidylserine. Journal of  Antimicrobial Chemotherapy. 2008. 61:103-110.
  12. Palit P., and Ali, N. Oral Therapy with Amlodipine and Lacidipine, 1,4-  Dihydropyridine  Derivatives Showing Activity against Experimental Visceral Leishmaniasis.  Antimicrobial Agents Chemotherapy. 2008.  52:374-377.
  13. Mazumder, S., Ravindran, R., Banerjee, A., Ali, N. Non-coding pDNA bearing immunostimulatory sequences co-entrapped with leishmanial antigens in cationic liposomes elicits almost complete protection against experimental visceral leishmaniasis in BALB/c mice. Vaccine. 2007. 25:8771-81.
  14. Saha, S., Mondal, S., Ravindran, R., Bhowmik, S., Modak, D., Mallick, S., Rahman, M., Kar, S., Goswami, R., Guha, SK., Pramanik, N., Saha, B., Ali, N. IL-10 and TGF-β mediated susceptibility in Post-kala-azar-dermal leishmaniasis: The significance of amphotericin B in the control of Leishmania donovani infection in India. Journal of Immunology. 2007. 179:   5592-5603.
  15. Bhowmick, S., Ravindran, R., and Ali, N. Leishmanial antigens in liposomes promote protective immunity and provide immunotherapy against visceral leishmaniasis via polarized Th1 response. Vaccine. 2007. 25: 6544-6556.
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Updated on 25th August'2010
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