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Infectious Diseases & Immunology Division

Dr. Debjani Mandal

Senior Scientist
PhD, Burdwan University, 1991
Contact - debjani@iicb.res.in, debjanimandal@hotmail.com

Current Research Interest

  • To understand the functional role of Transmembrane Proteins and Enzymes of Leishmania.
  • Biochemical and Molecular characterization of the transporter involved in metabolites and ion translocation.
  • Evaluation of Drug resistance mechanism of Leishmania.
Names of the group members including regular staff with designation and research fellows:
  Fellow/RA
   

List of important Publications:

  • Debjani Mandal, Samuel J. Rulli, Rajini Rao. (2003) Packing Interactions between transmembrane helices alter ion selectivity of the golgi Ca2+, Mn2+ ATPase PMR1. J. Biol. Chem. 278 (37) : 35292-35298.
  • Von-Khue Ton, Debjani Mandal, Cordelia Vahadji and Rajini Rao. (2002) Funtional Expression in Yeast of the Human Secretory Pathway Ca2+, Mn2+ ATPase Defective in Hailey Hailey Disease.  J. Biol. Chem. 277 (8): 6422-6427.
  • Mukherjee, T., Mandal, D. and Bhaduri, A. (2001) Leishmania Plasma membrane Mg2+ATPase is a H+/K+ Antiporter involved in Glucose Symport. J. Biol. Chem. 276 : 5563-5569.
  • Debjani Mandal, Thomas B. Woolf and Rajini Rao (2000).  Manganese Selectivity of Pmr1, the Yeast Secretory Pathway Ion Pump, is defined by residue Gln783 in transmembrane segment 6.  RESIDUES ASP778 IS ESSENTIAL FOR CATION TRANSPORT. J Biol. Chem275 (31) : 23933-23938.
  • Manual, Debjani, Mukherjee, Tanmoy., Sarkar, Sibaji., Majumdar, Sabita and Bhaduri,. A.N. (1997) The Plasma membrane Ca2+ ATPase of Leishmania donovani is an exrtusion pump for Ca2+. Biochem. J. (322): 251-257.
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Updated on 2003
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