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Chemistry Division

Dr. Surajit Ghosh

Principal Scientist

  • Ramanujan Fellow at CSIR-IICB (January 2011-till date)
  • Postdoctoral Fellow (July 2008-December 2010), European Molecular Biology Laboratory, Heidelberg, Germany
  • Doctoral Fellow (July 2004-June 2008), Indian Institute of Technology Kanpur, India 
  • Scientist (January 2001- July 2004) Syngene International Limited (BIOCON GROUP), Bangalore, India

Contact - sgiicb@gmail.com / sghosh@iicb.res.in

Contact Phone No. +91-33-24995872

Dr. Ghosh's Lab Website (Click)


  • Travel grant by DBT/ Wellcome Trust for attending “EMBO Global Exchange & the Wellcome Trust/DBT India Alliance meeting” at Barcelona (2010)
  • Alexander von Humboldt Fellowship (2010-2012)
  • Travel grant by BASF for attending in International Symposium “BASF Conference on Nanomaterials” in Singapore (2007)
  • Biocon Tribute award for important contribution (A Biocon India Group, 2002)

Current Research Interest

Interface between chemistry and biology:

  • Development of various platforms for studying bio-molecular interactions through surface modification, patterning and using liposome
  • Understanding kinesin mediated cargo (nanomaterial) transport using in vitro assay
  • Understanding role of small molecules and peptide in microtubule dynamics as well as intra-cellular microtubule networks
  • Understanding self-assembly of bio-inspired peptide and their interaction with membrane and tubulin

Grant: Approved by DST, India from 2013 onwards for three years.

Names of the group members including regular staff with designation and research fellows:

Position Available: PhD and Postdoctoral positions are available.
CSIR/UGC NET awardees with  a background in Organic Chemistry/ Biochemistry/Molecular Biology/ Biotechnology are welcome to apply.

Fellow/RA Staff Others
  1. Mr. Atanu Biswas, JRF
  2. Mr. Batakrishna Jana, JRF
  3. Mr. Abhijit Saha, JRF
  4. Mr. Prashant Kurkute, JRF

Our recent work in Front Cover Page.


List of important Publications(After Joining at CSIR-IICB):

18. Jyothi B Nair#, Saswat Mohapatra#, Surajit Ghosh*, Kaustabh K Maiti*. Novel Lysosome Targeted Molecular Transporter Built On Guanidinium-Poly-(propylene imine) Hybrid Dendron for Efficient Delivery of Doxorubicin into Cancer Cells. Chem.Commun. 2014, Just Accepted, doi: 10.1039/C4CC09829C.

17. AbhijitSaha, Saswat Mohapatra, Prashant Kurkute, Batakrishna Jana, Prasenjit Mondal, Debmalya Bhunia, Subhajit Ghosh and Surajit Ghosh*Interaction of Aβ peptide with tubulin causes inhibition of tubulin polymerization and apoptotic death of cancer cells . Chem. Commun. 2014, Just Accepted, doi: 10.1039/C4CC09390A.


16. Batakrishna Jana, Atanu Biswas, Saswat Mohapatra, Abhijit Saha and Surajit Ghosh.* Single functionalized graphene oxide reconstitutes kinesin mediated intracellular cargo transport, delivers multiple cytoskeleton proteins and therapeutic molecule into the cell. Chem. Commun. 2014, 50 (78), 11595-11598.

15. Rajdeep Chowdhury, Abhijit Saha, Amit Kumar Mandal, Batakrishna Jana, Surajit Ghosh,* and Kankan Bhattacharyya.* Excited State Proton Transfer in the Lysosome of Live Lung Cells: Normal and Cancer Cell. J. Phys. Chem. B, 2014, DOI: 10.1021/jp503804y.

14. Shruti Khanna, Batakrishna Jana, Abhijit Saha, Prashant Kurkute, Surajit Ghosh,* Sandeep Verma.* Targeting Cytotoxicity and Tubulin Polymerization by Metal-Carbene Complexes on a Purine Tautomer Platform. Dalton Transactions, 2014, 43, 9838-42.  

13. Rajdeep Chowdhury, Batakrishna Jana, Abhijit Saha, Surajit Ghosh,* and Kankan Bhattacharyya.* Confocal Microscopy of Cytoplasmic Lipid Droplets in a Live Cancer Cell: Number, Polarity, Diffusion and Solvation Dynamics. MedChemComm., 2014, 5, 536-539.

12. Atanu Biswas, Prashant Kurkute, Batakrishna Jana, Aparna Laskar and Surajit Ghosh.* Amyloid inhibitor octapeptide forms amyloid type fibrous aggregate and affect in microtubule motility. Chem. Commun., 2014, 50, 2604-7.

11. Atanu Biswas,‡Abhijit Saha,‡ Dhruba Ghosh, Batakrishna Jana and Surajit Ghosh.* Co- and distinct existence of Tris-NTA and biotin functionalities on individual and adjacent micropatterned surfaces generated by photo-destruction. Soft Matter, 2014, 10, 2341-45.
(Accepted as Inside Front Cover page)  (http://pubs.rsc.org/en/content/articlelanding/2014/sm/c3sm53000k#!divAbstract)

10. Batakrishna Jana, Goutam Mondal, Atanu Biswas, Indrani Chakraborty, Abhijit Saha, Prashant Kurkute and Surajit Ghosh.* Dual functionalised graphene oxide serves as a carrier for delivering oligo-histidine and biotin tagged biomolecules into cell. MacromolBiosci. 2013, 13, 1478-1484(Accepted in Front Cover).(http://onlinelibrary.wiley.com/doi/10.1002/mabi.201300129/abstract)

9. Abhijit Saha, Goutam Mondal, Atanu Biswas, Indrani Chakraborty, Batakrishna Jana and Surajit Ghosh.* In vitro reconstitution of a cellular like environment using liposome for amyloid beta peptide aggregation and its propagation. Chem. Commun., 2013, 49, 6119-6121. (Accepted in Front Cover).(http://pubs.rsc.org/en/content/articlelanding/2013/cc/c3cc41287c#!divAbstract)

8. Atanu Biswas, Abhijit Saha, Batakrishna Jana, Prashant Kurkute, Goutam Mondal and Surajit Ghosh.* Facile generation of biotin micropatterned surface by photo destruction serves as a novel platform for microtubule organisation and DNA hybridisation. ChemBioChem, 2013, 14, 689-694.(http://onlinelibrary.wiley.com/doi/10.1002/cbic.201300027/abstract)

7. Surajit Ghosh, Christian Hentrich, and Thomas Surrey.* Micropattern-Controlled Local Microtubule Nucleation, Transport, and Mesoscale Organization. ACS ChemBiol., 2013, 8, 673-678.(http://pubs.acs.org/doi/abs/10.1021/cb300583p)

List of important Publications(Before Joining at CSIR-IICB):

6. Maniraj Bhagawati,# Surajit Ghosh,# Annett Reichel, Klaus Froehner, Thomas Surrey, Jacob Piehler.* Organization of motor proteins into functional micropatterns fabricated by a photo-induced Fenton reaction. Angew. Chem. Int. Ed.  2009, 48, 9188-9191. Accepted as Hot Paper.

5. Surajit Ghosh, Arindam Mukherjee, Peter. J. Sadler.* Sandeep Verma.*Periodic Iron Nanomineralization in Human Serum Transferrin Fibrils. Angew. Chem. Int. Ed.2008, 47, 2217-2221. (Accepted as Very Important Paper, Inside Cover Page, Highlighted by: Nature India; C & E News; Angew. Chem., EurekAlert).

4. Surajit Ghosh, Sandeep Verma.* Templated growth of hybrid structures at peptide-peptide interface. Chem. Eur. J. 2008, 14, 1415-1419.

3. Surajit Ghosh, SukhmaniKaur Singh, Sandeep Verma.* Self-assembly and potassium ion triggered disruption of peptide-based soft structures. Chem. Commun. 2007, 22, 2296-2298.

2. Surajit Ghosh, Sandeep Verma.*Phased Fiber Growth in a Peptide Conjugate: Aggregation and Disaggregation Studies. J. Phys. Chem. B, 2007, 111, 3750-3757.

1. Surajit Ghosh, Meital Reches, Ehud Gazit,* Sandeep Verma.* Bioinspired design of nanocages by self-assembling triskelion peptide elements. Angew. Chem. Int. Ed. 2007, 46, 2002-2004 (Accepted as Inside Cover Page).

All Detailed list of Publication == >> Go


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Updated on 17th December 2014
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