Dr. P CHATTOPADHYAY

Current Research Interest

1. Synthesis of chiral medium ring heterocycles from carbohydrates/amino acid derived precursors (Chiron approach).
2. Development of synthetic methodology for the generation of benz-annulated medium ring heterocycles related to drug.
3. Synthesis and conformational studies of carbohydrate/ non-carbohydrate based Triazole-amide pseudo cyclic peptides.
4. Multicomponent synthesis.
5. Organic reactions in aqueous medium.

Names of the group members including regular staff with designation and research fellows: Staff Members Dr. Tapas Sarkar Extn. No.871 Senior Technical Officer-III(2)  Mr E. Padmanaban Extn. No.886 Senior Technical Officer- III (1) Mr Sandip Kundu Extn. No.917 Technical Assistant  Fellow / RA / PA Mr.Abhijit Ghorai SRF CSIR Mr.Sudipta Mitra SRF CSIR Miss Heena Darira (Niper MC) Miss Anu Raju (Niper MC)

List of important Publications:

1. Design and Synthesis of Regioisomeric Triazole/Amide Peptidomimetic Macrocycles and Their Dipole Moment Controlled Self-Assembly: Ghorai, A.; Padmanaban, E.; Achari,B.; Mukhopadhyay, C.; Chattopadhyay,P*.Chem Commun .48, 2012, 11975-78 (Impact factor 6.2)
2. Design and Synthesis of 1,2,3-Triazole-Fused Chiral Medium Ring Benzo-Heterocycles, Scaffolds Mimicking Benzolactams:  Adhikary,N. D.; Chattopadhyay, P*. J. Org. Chem., 77, 2012, 5399-5405. Impact factor 4.3)
3. Simultaneous Parallel and Anti-Parallel self–assembly in a Triazole /amide macrocycle conformationally homologous to D-,L-α-Amino Acid Based Cyclic Peptides: NMR and Molecualr Modeling Study: Ghorai, A.; Gayen, A.; Kulsi, G.; Padmanaban, E.; Laskar,A.; Achari, B.; Mukhopadhyay, C.; Chattopadhyay, P.* Org. Lett., 13, 2011, 5512-5515 (Impact factor 5.2).
4. Synthesis of Chiral Benzoxa(thia)zepine and Pyridoxazepine Derivatives Using Palladium-Catalyzed Intramolecular Arylamination Reaction: Adhikary, N. D. ; Chattopadhyay, P.*  Eur. J. Org. Chem. 2011, 7346-7354 (Impact factor 3.2).
5. Synthesis and biological evaluation of dibenz[b,f][1,5]oxazocine derivatives for agonist activity at κ-opioid receptor: Mitra, S; Banerjee, T. S.; Bhattacharya, D.; Hota, S. K.; das, S.; Chattopadhyay, P.* Eur. J. Med. Chem. 46, 2011 1713-1720 (Impact factor 3.2).
6. Palladium Catalyzed Intramolecular Aryl Amination Reaction: An Expeditious Approach to the Synthesis of Chiral Benzodiazocine Derivatives Adhikary, N. D. ; Chattopadhyay, P.*  Eur. J. Org. Chem. 2010, 1754-1762. (Impact factor 3.2)
7. A green chemical approach for the N-alkylation of aldoximes to form nitrones in organized aqueous media and their in situcycloaddition with olefins  Hota, S. K.;  Chatterjee, A; Bhattacharya, P. K.; Chattopadhyay, P.* Green Chemistry 11, 2009, 169-176. (Impact factor 5.48)
8. Palladium-catalyzed intramolecular C-O bond formation: A chiron approach to the synthesis of medium ring oxygen heterocycles: Neogi, A.; Majhi, T. P.; Achari, B.; Chattopadhyay, P.* Eur. J. Org. Chem. 2008, 330-336. (Impact factor 3.2)
9. Sequential Baylis-Hillman reaction and radical cyclization of furanosederivatives: expeditious approach to enantiopure benzofused nine-membered oxacycles: Neogi, A.; Majhi, T. P.; Ghosh S.; Mukherjee, A. K. Chattopadhyay, P.* Tetrahedron, 62, 2006, 12003-12010. (Impact factor 3)
10. Palladium mediated intramolecular aryl amination on furanose derivatives: An expedient approach to the synthesis of chiral benzoxazocine derivatives and tricyclic nucleosides: Neogi, A.; Majhi, T. P.; Mukhopadhyay, R; Chattopadhyay, P.* J. Org. Chem. 71,  2006, 3291-3294. (Impact factor 4.3)
11. A simple construction of chiral fused benzoxocine ring ethers from D(+) glucose by 8-endo aryl radical cyclization: Chattopadhyay, P.*; Mukherjee, M. Ghosh, S. Chem Commun. 1997, 2139-2140. (Impact factor 5.7)

Detail list of Publications upto November 2012 ==>> Click here