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Chemistry Division

Dr. Parasuraman Jaisankar, Ph.D., F.I.C.

Scientist EII
Ph.D. Jadavpur University, 1995
RCMS Fellow - With Nobel Laureate Prof. R. Noyori, & Prof. M. Kitamura, Japan, 2001-02.
DAAD Fellow – Ulm University, Germany, 1996-98.
Contact - jaisankar@iicb.res.in / pjaisankar@yahoo.com

Current Research Interest

  • Development of chiral ligands and their transition metal complexes for asymmetric organic transformations.
  • Synthesis of Lead Compounds and their analogues having various biological activities, with special focus on anticancer and anti-asthmatic, anti-microbial, and anti-inflammatory compounds.
  • Development of synthetic strategy for the generation of structurally unique bioactive molecules especially nitrogen heterocycles.
  • Identification and structure elucidation of antibiotics isolated from marine actinobacterium.Search for safe drugs from herbal sources.

 
Names of the group members including regular staff with designation and research fellows:
Fellow/RA

Staff
Others
  1. Dr. (Mrs) Sumanlata Pillai, RA(ICMR)
  2. Miss. Churala Pal, SRF
  3. Mr. Debkumar Nandi, SRF
  4. Mrs. Ramesh Kumari, SRF
  5. Mr. Sanjit Kumar Mahato, JRF
  6. Miss. Madhumita Mandal, JRF
  7. Miss. Tulika Mukherjee, Project Asst.
  8. Mr. Jayaraman Vinayagam, Project Asst.
    

List of important Publication:

  1. Lewis Acid-Catalyzed One-pot, Three-Component Route to Chiral 3,3′-Bipyrroles: S. Dey, C. Pal, D. Nandi, V. S. Giri, M. Zaidlewicz, M. Krzeminski, L. Smentek, B. A. Hess, Jr., J. Gawronski, M. Kwit, N. J. Babu, A. Nangia, P. Jaisankar, Organic Lett. 2008, 10, 1373-1376.
  2. Asymmetric synthesis of N-1-(heteroaryl)ethyl-N-hydroxyureas: Mariusz J. Bosiak, Marek P. Krzemiński, P. Jaisankar, and Marek Zaidlewicz, Tetrahedron: Asymmetry, 2008, 19, 956-963.
  3. Asymmetric synthesis of N-substituted N-hydroxyureas: Krzysztof Z. Łączkowski, Marcin M. Pakulski, Marek P. Krzemiński, P. Jaisankar and Marek Zaidlewicz, Tetrahedron: Asymmetry, 2008, 19, 788-795.
  4. An insight into the mechanism of inhibition of unusual bi-subunit topoisomerase I from Leishmania donovani by 3,3´-diindolylmethane, a novel DNA topoisomerase I poison with a strong binding affinity to the enzyme: A. Roy, B. B. Das, A. Ganguly, S. Bose Dasgupta, N. V. M. Khalkho, C. Pal, S. Dey, V. S. Giri, P. Jaisankar, S. Dey and H. K. Majumder, Biochem. J. 2008, 409, 611–622.
  5. Enhanced Production of Antimicrobial Compounds by Three Salt-Tolerant Actinobacterial Strains Isolated from the Sundarbans in a Niche-Mimic Bioreactor, S. Sarkar, M. Saha, D. Roy, P. Jaisankar, S. Das, L. Gauri Roy, R. Gachhui, T. Sen and J. Mukherjee,  Marine Biotch. 10.1007/s10126-008-9090-0 (D.O.I.) (2008).
  6. Indium trichloride catalyzed efficient one-pot synthesis of highly substituted Furans: S. Dey, D. Nandi, P. K. Pradhan, V. S. Giri and P. Jaisankar, Tetrahedron Lett. 2007, 48, 2573-2575.
  7. Eco-friendly synthesis and study of new plant growth promoters: 3,3´- Diindolylmethane and its derivatives: C. Pal, S. Dey, S. K. Mahato, J. Vinayagam, P. K. Pradhan, V. S. Giri, P. Jaisankar, T. Hossain, S. Baruri, D. Ray and S. Mandal Biswas, Bioorganic & Medicinal Chemistry Lett. 2007, 17, 4924-4928.
  8. Production and purification of an antimicrobial substance inhibiting multiple drug resistant bacteria from a salt-tolerant marine actinobacterium isolated from the Bay of Bengal, M. Saha, P. Jaisankar, S. Das, K. Kr. Sarkar, S. Roy, S. E. Besra, J. R. Vedasiromani, D. Ghosh, B. Sana and J. Mukherjee, Biotechnol. Lett.2006, 28,1083.
  9. Biological relevance of host plant-derived terpenoid in the cocoons of the tropical tasar silkworm Antheraea mylitta, P.C. Bindu, P. Jaisankar, F. Hauer, H.O. Gutzeit, and S.C. Kundu, Biochem. Syst. Ecol.2006, 34, 698.
  10. First Indium trichloride catalysed self addition of indoles: One pot synthesis of indolylindolines: B. Pal, V. S. Giri, P. Jaisankar, Catalysis Commun. 2005, 6, 711.
  11. InCl3-HMTA as a Methylene Donor: One-Pot Synthesis of Diindolylmethane (DIM) and Its Derivatives: P. K. Pradhan, S. Dey, V. S. Giri, P. Jaisankar, Synthesis 2005, 1799.
  12. Unusual formationof β- carboline dimmers under Bischler Napieralski reaction Conditions: An old reaction with a new direction:  B. Pal, P. Jaisankar, V. S. Giri, S. Mondal, M. Mukherjee, Tetrahedron Lett., 2004, 45, 6489.
  13. First tiphenylphosphine promoted reduction of maleimides to succinimides: B. Pal, P. K. Pradhan, P. Jaisankar, V. S. Giri, Synthesis, 2003, 1549.
  14. Microwave assisted Pictet-Spengler and BischlerNapieralski reactions: B. Pal, P. Jaisankar, V. S. Giri, Synth. Commun. 2003, 33, 2339.
  15. Synthetic studies in Indolo[2,3-a]quinolizidine system: V. S. Giri, P. Jaisankar, R. K. Manna, J. N. Shoolery, P. Keifer, Tetrahedron, 1995, 51, 10101.
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