Dr. G. Suresh Kumar
Scientist
E-II
PhD, University of Delhi, 1988
Contact - gskumar@iicb.res.in
Current Research
Interest
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Micro
RNA-mRNA interaction.
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DNA
and RNA polymorphism.
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Interaction
of Drugs with DNA and RNA: Molecular basis of
the antitumor action of alkaloids through
biophysical studies.
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Binding
of a number of medically important natural
products and small molecules to polymorphic
nucleic acid structures like duplex, triplex and
quadruplexes.
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Photochemistry
and photobiology of alkaloids.
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| Names of the group
members including regular staff with designation
and research fellows: |
| Fellow/RA |
Staff |
- Mr. Maidul Hossain, SRF-UGC
- Ms. Ishita Saha, JRF-CSIR
- Mr. Anirban Basu, JRF-UGC
- Ms. Puja Paul, JRF-CSIR
- Ms. Asma Asmeen Khan, JRF-UGC
- Ms. Abhi Das,JRF-CSIR
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- Dr. R.C. Yaday, Scientist
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List of important
Publications:
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Saha, I, Hossain M. and Suresh Kumar, G*. (2010) Base pair specificity and energetics of binding of phenazinium molecules phenosafranin and safranin-O to deoxyribonucleic acids: A comparative study. Phys. Chem. Chem. Phys. (in press).doi: doi:10.1039/C001062F.
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Bhadra, K. and Suresh Kumar, G*. (2010) Therapeutic potential of Nucleic acid binding isoquinoline alkaloids: Binding aspects and implications for drug design. Med. Res. Rev. (in press).doi:10.1002/med.20202.
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Hossain, M., and Suresh Kumar, G*. (2010) Thermodynamic profiles of the DNA binding of benzophenanthridines sanguinarine and ethidium: A comparative study with sequence specific polynucleotides. J. Chem. Thermodyn. 42,1273-1280.
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Giri, P. and Suresh Kumar, G*. (2010) Isoquinoline alkaloids and their binding with polyadenylic acid: potential basis of therapeutic action. Mini Rev. Med. Chem. 10(7), 568-577.
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Roy Chowdhury, S., Islam M. M. and Suresh Kumar, G*, (2010) Binding of the benzophenanthridine alkaloid sanguinarine to double stranded RNA polynucleotides: New insights into the structural aspects and energetics of interaction. Mol. BioSystems 6, 1265-1276.
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Saha, B., Islam, M., Paul, S., Samanta, S., Ray, S., Santra, C.R., Choudhury, S.R., Dey, B, Das, A., Ghosh, S., Mukhopadhyay. S., Suresh Kumar, G. and Karmakar, P. (2010) DNA binding ability and hydrogen peroxide induced nuclease activity of a novel Cu(II) complex with malonate as primary ligand and protonated 2-amino-4-picoline as counter ion. J. Phys. Chem. B.114, 5851-5861.
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Maiti, M. and Suresh Kumar, G. (2010) Polymorphic nucleic acid binding of bioactive isoquinoline alkaloids and their role in cancer, J. Nucleic Acids, 2010 (2010), Article ID 593408, 1-23.
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Pandya, P., Islam, M.M. and Suresh Kumar, G., Jayaram, B. and Kumar, S. (2010) DNA minor groove binding of small molecules: Experimental and computational evidence. J. Chem. Sci. 122, 247-257.
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Paul, P., Hossain, M., Yadav, R. C. and Suresh Kumar, G*. (2010) Base specificity and energetics of the interaction of thionine to deoxyribonucleic acids: Spectroscopic and calorimetric approach. Biophys. Chem. 148, 93-103.
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Giri, P. and Suresh Kumar, G. (2010) Molecular recognition of poly(A) by protoberberine alkaloids: In vitro biophysical studies and biological perspectives.Mol. Biosystems 6, 81-88.
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