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Chemistry Division

Dr. Chinmay Chowdhury
Principal Scientist

Ph.D., Jadavpur University (1998)
Postdoctoral Research:
a) University of Kentucky, Lexington, USA (1999-2000)
b) University of California, San Diego, USA (2000-2002)
Contact - chinmay@iicb.res.in, cchinmay2@yahoo.com

Current Research Interest

  • Isolation & identification of bioactivity guided extracts, fractions and unique bioactive molecules from Indian medicinal plants
  • Up scaling & process development for value added natural products
  • Preparation of analogue library of lead phytomolecules through synthesis
  • Technology development on novel phytopharmaceutials
  • Palladium-catalyzed synthesis of novel nitrogen-heterocycles of biological importance.
 
Names of the group members including regular staff with designation and research fellows:
  Fellow/RA
 
  1. Mr. Kaushik Brahma (SRF, CSIR)
  2. Mr. Bimolendu Das (JRF,CSIR)
  3. Miss Sanjukta Mukherjee (JRF, DST Project), E Mail : M_SANJUKTA10@yahoo.co.in
  4. Priyanka Kundu (JRF, UGC)
  5. Biswajit Chakraborty 

List of important Publications:

  1. K. Brahma, B. Achari and C. Chowdhury:  “Facile synthesis of [1,2,3]-triazole-fused isoindolines, tetrahydroisoquinolines, benzoazepines and benzoazocines  by palladium-copper catalysed heterocyclisation”,  Synthesis, 2012, in press.
  2. P. Das, D. Kumar, R. Roy, C. Chowdhury, M. Chatterjee: “Andrographolide analogue induces apoptosis and autophagy mediated cell death in U937 cells”, Eur. J. Cancer, 2012, 48, suppl.5, S156.
  3. C. Chowdhury,  B. Das, S. Mukherjee and B. Achari : “Palladium-catalyzed approach for the general synthesis of (E)-2-arylmethylidene-N-tosylindolines and (E)-2-arylmethylidene-N-tosyl/nosyltetrahydroquinolines: Acess to 2-Substituted Indoles and Quinolines”,  Journal of Organic Chemistry , 2012, 77, 5108-5119.
  4. K. Brahma, A. K. Sasmal and C. Chowdhury: “An efficient strategy for the general synthesis of 3-aryl substituted pyrazolo[5,1-c][1,4]benzoxazines and pyrazolo[1,5-a][1,4]benzodiazepin-6(4H)-ones”,  Organic  & Biomolecular Chemistry , 2011, 9, 8422-8429.
  5. C. Chowdhury, S. Mukherjee, B. Chakraborty and B. Achari: “A rapid and facile method for the general synthesis of 3-aryl substituted 4,5,6,7-tetrahydro[1,2,3]triazolo[1,5-a]pyrazines and their ring fused analogues”, Organic & Biomolecular Chemistry, 2011, 9, 5856-5862.
  6. C. Chowdhury,  A. K. Sasmal and   B. Achari : “An expedient and facile  route for the general synthesis of 3-aryl substituted 1,2,3-triazolo[1,5-a][1,4]benzodiazepin-6-ones and 1,2,3-triazolo[1,5-a][1,5]benzodiazocin-7-ones”, Organic & Biomolecular Chemistry, 2010, 8, 4971-4977.
  7. C. Chowdhury,  K. Brahma, S. Mukherjee  and A. K. Sasmal : “Totally regio- and stereoselective synthesis of (E)-3-arylidene-3,4-dihydro-2H-1,4-benzoxazines under palladium catalyst”, Tetrahedron Letters, 2010, 51, 2859-2861.
  8. B. Das,  C. Chowdhury,  D. Kumar,  R. Sen,  R. Roy, P. Das and  M. Chatterjee:               “Synthesis, cytotoxicity, and structure-activity relationship (SAR)  studies of andrographolide analogues as  anti-cancer agent”,  Bioorganic & Medicinal Chemistry Letters; 2010,  20, 6947-6950.
  9. C.Chowdhury, S. Mukherjee, B. Das and B. Achari : "Expedient and rapid synthesis of 1,2,3-triazolo [5,1-c] morpholines through palladium-copper catalysis", Journal of Organic Chemistry,2009, 74, 3612-3615.
  10. C. Chowdhury, A. Sasmal and P. K. Dutta : "Efficient synthesis of 1,2,3-triazolo [5,1-c][1,4] benzoxazines through palladium-copper catalysis", Tetrahedron Letters,2009, 50, 2678-2681.

Detail list of Publications upto November 2012 ==>> Click here

 

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Updated on 11th December 2012

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