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Cell Biology & Physiology Division

Dr. Tuli Biswas

Senior Principal Scientist
PhD, Calcutta University, 1984
Contact -tulibiswas@iicb.res.in

Current Research Interest

  • NO  regulated  plasma redox  imbalance in visceral leishmaniasis.
  • Development of antileishmanial therapy based on metabolic intervention in both  host  and pathogen.
  • Mechanism   of  hemolysis  in  chronic  arsenic exposure.
  • Therapeutic efficacy of plant products from natural sources against hepatocellular apoptosis
Names of the group members including regular staff with designation and research fellows:
Fellow/RA/PA Staff
  1. Samir Mandal, SRF(CSIR)
  2. Avik Sarkar, PA


List of important Publications:

  1. Mandal, S., Mukherjee, S., Dutta Chowdhury, K., Sarkar, A., Basu, K., Paul, S., Karmakar, D., Chatterjee, M., Biswas, T., Sadhukhan, G.C., Sen, G. .(2012) S-allyl cysteine in combination with clotrimazole  downregulates Fas induced apoptotic events in erythrocytes of mice exposed to lead. Biochimica et Biophysica Acta. 1820, 9-23
  2. Dutta Chowdhury, K., Sen, G., Sarkar, A., Biswas, T.(2011) Role of endothelial dysfunction in modulating the plasma redox homeostasis in visceral leishmaniasis.Biochimica et Biophysica Acta. 1810, 652–665.
  3. Dutta Chowdhury, K., Sen, G., Biswas, T: Regulatory role of nitric oxide in the  reduced survival of erythrocytes in visceral leishmaniasis. Biochimica et  Biophysica Acta. 1800, 964–976 , 2010
  4. Roy, D.N., Mandal, S., Sen, G., Mukhopadhyay, S and Biswas, T: 14- Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor alpha- induced apoptosis through calcium-dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway. British Journal of Pharmacology. 160, 1823–1843, 2010
  5. Biswas, D., Sen, G., Biswas, T: Reduced cellular redox status induces 4- hydroxynonenal-mediated caspase 3 activation leading to erythrocyte death during chronic arsenic exposure in rats. Toxicology and Applied Pharmacology. 244, 315–327, 2010   
  6. Roy,D.N.,Mandal,S.,Sen,G.,Biswas,T: Superoxide anion mediated mitochondrial dysfinction leads to hepatocyte apoptosis preferentially in theperiportal region during copper toxicity in rats. Chemico-Biological Interactions, 182, 136-147, 2009
  7. Saha Roy,S., Dutta Chowdhury,K., Sen,G., Biswas,T: Oxidation of hemoglobin and redistribution of band 3 promote erythrophagocytosis in  visceral leishmaniasis. Molecular and Cellular Biochemistry, 321, 53-63, 2009
  8. Biswas, D., Banerjee, M., Sen, G., Das, J.K., Banerjee, A., Sau, T.J., Pandit, S., Giri, A.K., Biswas, T: Mechanism of rythrocyte death in human population  exposed to arsenic through drinking water. Toxicology and Applied Pharmacology, 230, 57-66, 2008
  9. Sen, G., Mukhopadhyay,S., Ray, M., Biswas,T: Quercetin interferes with  iron metabolism in Leishmania donovani and targets ribonucleotide reductase  to exert leishmanicidal activity.  Journal of Antimicrobial Chemotherapy,  61, 1066-1075, 2008      
  10. Sen,G., Biswas, D., Ray, M., Biswas, T: Albumin-quercetin combination  offers a therapeutic advantage in the prevention of reduced survival of  erythrocytes in visceral leishmaniasis. Blood Cells, Molecules & Diseases, 39, 245-254, 2007
  11. Sen,G.,Mandal,S., Saha Roy,S., Mukhopadhayay,S.,Biswas,T: Therapeutic use of quercetin in the control of infection and anemia associated with  visceral leishmaniasis. Free Radical Biology and Medicine, 38, 1257-1264, 2005
  12. Saha Roy,S., Sen,G., Biswas,T: Role  of sulfhydryl groups in band 3 in the inhibition of phosphate transport across erythrocyte membrane in visceral  leishmaniasis. Archives of Biochemistry and Biophysics, 436, 121-127,2005.


Detail list of Publications upto March'2012 ==>> Click here

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Updated on 23rd April'2012
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