Cancer Biology & Inflammatory Disorder Division

Dr. Padma Das

PhD, Jawaharlal Nehru University, New Delhi

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Principal Scientist

Current Research Interest

            • Anticarcinogenic effects of Andrographis paniculata and its derivative in Human leukemic cell line
            • Studies on Bioactive compounds from natural and synthetic sources
            • Programmed cell death of cancer cell and signaling
            • Anticarcinogenic effect of edible mushroom

Names of the group members including regular staff with designation and research fellows





  1. Deepak Kumar, SRF/CSIR
  2. Ms. Rajneeta Roy, SRF/CSIR Debasmita Dutta , JRF/DBT

List of important Research Articles

  1. Saha P, Sen R, Hariharan C, Kumar D, Das P, Chatterjee M. Berberine chloride causes a caspase-independent, apoptotic-like death in Leishmania donovani promastigotes- Free Radical Research, 43 (11), 1101-10, 2009.
  2. Das B, Chowdhury C, Kumar D, Sen R, Roy R, Das P, Chatterjee M. Synthesis, cytotoxicity, and structure–activity relationship (SAR) studies of andrographolide analogues as anti-cancer agent. Bioorganic & Medicinal Chemistry Letters, 20, 6947-50, 2010.
  3. Sarkar A, Saha P, Mandal G, Mukhopadhyay D, Roy S, Singh SK, Das S, Goswami RP, Saha B, Kumar D, Das P, Chatterjee M. Monitoring of intracellular nitric oxide in Leishmaniasis; its applicability in patients with Visceral Leishmaniasis., Cytrometry, Part A, 79A, 35-45, 2011
  4. M. Mandal, D. Kumar, R. Roy, R, Sen, P. Das, M. Chatterjee, P. Jaisankar,   Regioselective one pot synthesis of bioactive 3, 3’-diindolylethylene derivatives and study  of their cytotoxic activity. Bioorg. Med. Chem. Lett. 21: 3084-3087.2011
  5. Manna A, Saha P, Sarkar A, Mukhopadhyay D, Bauri AK, Kumar D, Das P,  Chattopadhyay S, Chatterjee M. Malabaricone-A induces apoptosis in U937 cells via  increased generation of reactive oxygen species. PLoS One 2012.
  6. Roy R, Kumar D, Chakraborty B, Chowdhury C, Das P .Apoptotic and Autophagic   Effects of Sesbania grandiflora Flowers in Human Leukemic Cells. PLoS One 8(8):   e71672.: 2013.
  7. B. Chakraborty, D. Dutta, S. Mukherjee, S. Das, N. C. Maiti, P. Das and C. Chowdhury. “Synthesis and biological evaluation of a novel betulinic acid derivative as inducer of apoptosis in human colon carcinoma cells (HT-29)”, European Journal of Medicinal Chemistry, 2015, in press (doi no: 10.1016/j.ejmech.2015.07.035
  8. D. Dutta, A. Sarkar, B. Chakraborty, C. Chowdhury and P. Das. “Induction of apoptosis by a potent betulinic acid derivative in human colon carcinoma HT-29 cells”, International Journal of Scientific and Research Publications, February 2015, vol. 5, issue 2, ISSN 2250-3153.
  9. D. Kumar, B. Das, R. Sen, P. Kundu, A. Manna, A. Sarkar, C. Chowdhury, M. Chatterjee, P Das*: Andrographolide analogue induces apoptosis and autophagy mediated cell death in U937 cells by inhibition of PI3K/Akt/mTOR pathway , PLoS ONE, 2015, In press
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Updated on10th August, 2015

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